Main Outcomes and Measures Clinical data were extracted from electronic medical records, and data of all neurologic symptoms were checked by 2 trained neurologists. The study included 214 consecutive hospitalized patients with laboratory-confirmed diagnosis of severe acute respiratory syndrome coronavirus 2 infection. Data were collected from January 16, 2020, to February 19, 2020, at 3 designated special care centers for COVID-19 (Main District, West Branch, and Tumor Center) of the Union Hospital of Huazhong University of Science and Technology in Wuhan, China. Objective To study the neurologic manifestations of patients with COVID-19.ĭesign, Setting, and Participants This is a retrospective, observational case series. However, to our knowledge, it has not been reported that patients with COVID-19 had any neurologic manifestations. Several studies have described typical clinical manifestations including fever, cough, diarrhea, and fatigue. Importance The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, is serious and has the potential to become an epidemic worldwide. Only then can the general public be truly informed before consenting to a potentially toxic medication regimen. When we have national TV commentators (Chris Cuomo) publicly describing their own personality changes with hallucinations while experiencing COVID-19, it's important that we know more about the actual source for these symptoms. All 3 of these medications have been implicated on occasion as possible sources of most of the CNS and PNS symptoms the authors describe in their article. I've also seen mention of parenteral corticosteroids. The media and some literature mention the use of the combination of hydroxychloroquine and azithromycin for Coronavirus Disease. I was unable to see any data in this article documenting which medications the cited patients were taking. Not infrequently, the source for all or at least some of these symptoms was prescribed medication and their side effects. In my role as a consultation liaison psychiatrist to a busy medical in-patient service, I frequently encountered unusual neurological and psychiatric (delirium) symptoms in very ill medical or post surgical patients. I have concerns about the conclusions drawn by Mao, Jin, Wang, et al in this article.
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